Hypersegmented neutrophil with megaloblastic anemia on smear

  • Here is a hypersegmented neutrophil that is present with megaloblastic anemias. There are 8 lobes instead of the usual 3 or 4.
  • Such anemias can be due to folate or to B12 deficiency.
  • The size of the RBC’s is also increased (macrocytosis, which is hard to appreciate in a blood smear).
Hyper Segmented Neutrophil

Hyper Segmented Neutrophil

 

  • This hypersegmented neutrophil is present along with macro-ovalocytes in a case of pernicious anemia. Compare the size of the RBC’s to the lymphocyte at the lower left center.
Hyper Segmented Neutrophil and Macrocytes

Hyper Segmented Neutrophil and Macrocytes

Source: http://library.med.utah.edu

 


Medical Laboratory Doctor

Share This Post

Related Articles

Leave a Reply

You must be Logged in to post comment.

© 2025 Medical Laboratories. All rights reserved. Site Admin · Entries RSS · Comments RSS
Powered by WordPress · Powered by Medical Labs