How to perform Manual Differential Count
LAB OBJECTIVE
To determine the relative number of each type of white cell present in the blood by performing differential cell counts on five relatively normal blood smears ...
The criteria of a good blood film
Free from holes caused by grease or dirt on the slide.
Not wavy film due to jerky movement during spreading.
Free from clear streaks resulted from chipped edge of the spreader ...
Platelet Clumping or Aggregation
the clump of platelets on peripheral blood smear are usually duo to poorly anticoagulated blood or In vitro artifact caused by EDTA or cold and leads to false low platelet count.
MegaKaryocyte Morphology
Megakaryocytes are among the largest cells in the bone marrow. The nuclei generally have multiple lobes, and the cytoplasm is granular. Occasionally platelets can be seen “budding” ...
Erythrocyte Sedimentation Rate (ESR)
The erythrocyte sedimentation rate (ESR), also called a sedimentation rate or Biernacki Reaction, is the rate at which red blood cells sediment in a period of 1 hour.
It is ...
Large Granular Lymphocyte on a Smear
A type of white blood cell that contains granules with enzymes that can kill tumor cells or microbial cells.
Megakaryoblast Morphology
Megakaryoblast :It’s is a precursor cell , which in turn becomes a megakaryocyte during haematopoiesis. It is the beginning of the thrombocytic series.
Size: 7 – 35 ...
Gray platelet syndrome (GPS)
The gray platelet syndrome (GPS) is a rare inherited disorder characterized by mild to moderate bleeding tendency, moderate thrombocytopenia, and a marked decrease or absence of platelet ...




