Summary of Abnormal Red Blood Cell Morphologies and Disease States
Before we start with the abnormal morphologies, let’s talk about normal morphology of Red Blood Cells.
Normal mature RBC are biconcave, round discs that are about 6 – 8 in ...
Smear from patient with Multiple Myeloma (M.M)
Smear from patient with Multiple Myeloma display an abundance of plasma cells.
RBC will often be seen in rouleaux formation stacked like poker chips.
Multiple myeloma (M.M) is ...
Autoagglutination vs Rouleaux formation
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen in Waldenström’s macroglobulinemia, cold agglutinin disease and Infection ...
rouleaux formation
The RBC’s here have stacked together in long chains. This is known as “rouleaux formation” and it happens with increased serum proteins, particularly fibrinogen and ...
Erythrocyte Sedimentation Rate (ESR)
The erythrocyte sedimentation rate (ESR), also called a sedimentation rate or Biernacki Reaction, is the rate at which red blood cells sediment in a period of 1 hour.
It is ...
Rouleaux Formation blood smear
The RBC’s here have stacked together in long chains. This is known as “rouleaux formation” and it happens with increased serum proteins, particularly fibrinogen and ...
