Spur cell RBC known as Acanthocyte

Spur cell RBC (Acanthocyte)

  • May be smaller or the size of a normal RBC
  • Irregular narrow-base sharp projections of red cell membrane (looking like cowboy boot spurs)

Increased in:

  • End stage Liver disease (Cirrhosis)
  • Abetalipoproteinemia
  • McLeod or Lu blood group phenotype
  • Post-splenectomy
  • Microangiopathic Hemolytic Anemia (as seen in DIC, TTP and HUS)
  • Artifact
Acanthocyte

Acanthocyte

Acanthocytes on a Blood Smear

Acanthocytes on a Blood Smear

Acanthocytes - this blood smear taken from patient with Abetalipoproteinemia

Acanthocytes – this blood smear taken from patient with Abetalipoproteinemia

 

 

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