Flame Cell

  • Flame cells are plasma cells with a distinctive pinkish hue in the outer rim of the cytoplasm. This appearance is thought to be the result of precipitated immunoglobulin. These cells can be found in plasma cell dyscrasias as well as cases of chronic infection or inflammation.
Flame cell

Flame cell

  • Certain paraproteins (especially IgA) can impart a red-magenta hue to the peripheral of neoplastic plasma cells giving rise to the so-called “flame cells” as seen in this case of IgA myeloma.
The Flame Cell

The Flame Cell



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