Giant Langhans Cell and Mycobacterium tuberculosis

  • Mycobacterium tuberculosis organisms are identified by their red color on acid-fast staining (Ziehl–Neelsen stain)
Mycobacterium tuberculosis (acid-fast stain rods)

Mycobacterium tuberculosis (acid-fast stain rods)

 

  • The granulomas of tuberculosis tend to contain necrosis (“caseating tubercules“)
  • these granuolomas contain Langhans giant cells,which have a “horseshoe” patern of nuclei
Tuberculosis Granuloma and Giant multinucleated cell

Tuberculosis Granuloma and Giant multinucleated cell

multinucleated giant cells of the Langhans type

multinucleated giant cells of the Langhans type

 


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