Poikilocytosis and RBC inclusions associated with asplenic patients

  • The RBC in the center of the field contains several Howell-Jolly bodies, or inclusions of nuclear chromatin remnants. There is also a nucleated RBC just beneath this RBC. Abnormal and aged RBC’s are typically removed by the spleen. The appearance of increased poikilocytosis, anisocytosis, and RBC inclusions suggests that a spleen is not present (asplenic patients).
Howell-Jolly bodies and NRBC

Howell-Jolly bodies and NRBC



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