Chronic lymphocytic leukemia vs Chronic myeloid leukemia
(C) – Chronic lymphocytic leukemia, peripheral blood smear: In CLL, the lymphocytes are excessively fragile. These lymphocytes are easily destroyed during slide preparation, forming ...
Acute Lymphocytic Leukemia (ALL) vs Acute Myelocytic Leukemia (AML)
(A) – Acute lymphocytic leukemia (ALL), peripheral blood smear, mostly affects children less than 10 years of age.
(B) – Acute myelocytic leukemia (AML) with Auer rods ...
Autoagglutination vs Rouleaux formation
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen in Waldenström’s macroglobulinemia, cold agglutinin disease and Infection ...
Feathered edge of peripheral blood smear
Quick scan on low power through entire slide for adequate distribution of cells then Check for platelets clumping & atypical cells at feathered edge. (if there are platelets clumping ...
How to make EDTA Bulbs ?
First add 4 mg of either disodium or dipotassium EDTA salt to 100 ml of deionized water. then add 0.2 ml of this solution to clean vials, then put these vials in incubator or hot air ...
P-LCR Parameter – Platelet large cell ratio
P-LCR means Platelet large cell ratio and it’s calculated in automated blood analyzers using this formula:
P-LCR = P-LCC/PLT.
PLT = Total Platelets Count.
P-LCC = platelets ...
fibrin strands with platelets in a smear
Conditions which cause platelet activation and aggregation in a sample (or a patient) may also promote fibrin formation by activation of the coagulation cascade. Shown above is a ...
Pyknocyte (Blister Cell)
It’s mature red blood cell with a clearing on one side and a concentrated area of hemoglobin on the other side
Clinical Conditions:
Infantile pyknocytosis
Infantile viremia
G6PD ...
chronic myeloid leukemia
Chronic myelogenous leukemia (also called chronic myeloid leukemia) is a rare cancer that affects bone marrow. That’s where blood cells are produced.
CML leads to the production ...
Chronic neutrophilic leukemia
Chronic neutrophilic leukemia :
The peripheral blood smear shows an absolute neutrophilia without the significant left shift, vacuolization, or toxic granulation usually associated ...
Hemoglobin C Diease and Trait laboratory diagnosis
Hemoglobin C (HbC) is an abnormal hemoglobin in which substitution of a glutamic acid with a lysine at the 6th position of the β-globin chain
This mutation is either heterozygous ...
Poikilocytosis and RBC inclusions associated with asplenic patients
The RBC in the center of the field contains several Howell-Jolly bodies, or inclusions of nuclear chromatin remnants. There is also a nucleated RBC just beneath this RBC. Abnormal ...
