- P-LCR means Platelet large cell ratio and it’s calculated in automated blood analyzers using this formula:
- P-LCR = P-LCC/PLT.
- PLT = Total Platelets Count.
- P-LCC = platelets larger than 12 fl and smaller than 30fl.
- Note: fL= femtoliter which is is the metric unit of volume equal to 10−15 litres.
- Increased percentage of large platelets (P-LCR) is observed in patients with Hyperlipidaemia and suggest possible risk of thrombosis.
- An increase in P-LCR + MPV + PDW has been observed in autoimmune thrombocytopenic purpura.
- MPV (mean platelet volume) – the average volume of platelets (normal 10.7 PL).
- PDW the relative width of the distribution of platelets in volume index of the heterogeneity of platelets.