a 30 year-old female diagnosed with sickle cell anemia. “Sickle cell anemia (Hb SS disease) is caused by inheritance of two ßs genes and is the most serious of the sickling syndromes. The natural history is characterized by a triad of chronic hemolytic anemia, vasoocclusive crises, and vulnerability to infection. The most commanding and disheartening of these afflictions are the vasoocclusive crisis, which gradually consume the patient, organ by organ, through the destructive and debilitating effects of cumulative infarctions