Summary of Abnormal Red Blood Cell Morphologies and Disease States

Before we start with the abnormal morphologies, let’s talk about normal morphology of Red Blood Cells. Normal mature RBC are biconcave, round discs that are about 6 – 8 in ...
IDA

Microcytosis

The term ‘microcytosis’ means small red cells. The three main causes are iron deficiency, some cases of the anemia of chronic disease, and the thalassemia syndromes. Sideroblastic ...

CBC diagram iron deficiency anemia

This is CBC diagram from patient with iron deficiency anemia, notice that: Hemoglobin, Hematocrit is decreased —> Anemia MCV is low —> Microcytic Anemia MCH is low ...
Hypochromic and Microcytic Red Cells

Hypochromic microcytic anemia on peripheral smear

This is hypochormic microcytic anemia condition Hypochormic as central pallor zone increased in most red cells Microcytic as cells are smaller than normal Anisocytosis (variation in ...
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