Regulation of RBC Production

Tissue oxygenation regulates RBC production. If the amount of oxygen transported to the tissues decreases, the rate of RBC production increases. The Feedback Mechanism: Tissue hypoxia ...

Formation of RBCs

An erythrocyte (erythro = red) is a fully mature red cell found in the peripheral blood. Although highly specialized, it is little more than a small bag – a membrane surrounding a ...

Reticulocytes smear

Supravital stain of a smear of human blood from a patient with hemolytic anemia. The reticulocytes are the cells with the dark blue dots and curved linear structures (reticulum) in ...

Summary of Abnormal Red Blood Cell Morphologies and Disease States

Before we start with the abnormal morphologies, let’s talk about normal morphology of Red Blood Cells. Normal mature RBC are biconcave, round discs that are about 6 – 8 in ...
Reticulocytes

Reticulocytes using vital stain

In the presence of some anemias, the body increases production of red blood cells (RBCs), and sends these cells into the bloodstream before they are mature. These slightly immature ...
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