- Decreased RBC size and Hemoglobin content (MCH) and concentration (MCHC) and increased central zone of pallor for more than the third of cell diameter.
- Microcytic Hypochromic Anemia seen in in Iron deficiency, thalasemia and Anemia of chronic disease.
Increased of RBC central pallor
Microcytic Hypochromic Anemia smear
Iron deficiency anemia blood smear – Notice the RBC size is smaller than the nucleus of small lymphocyte
CBC Report of Iron deficiency anemia patient
Peripheral blood smear of Thalassemia patient
CBC Report of Thalassemia patient