NRBCs and Howell Jolly body

A Howell Jolly body is seen in one red cell (A). Also present are two nucleated red blood cells (B).

Nucleated red blood cells (NRBCs): they may look at fist similar to small mature lymphocytes but a careful comparison reveals clear differences.

Nucleated red cells have a moderate amount of pink cytoplasm, with a central nucleus and clumped chromatin, often with some open spaces. Mature lymphocytes have a thin rim of blue cytoplasm, a nucleus with dark chromatin (no open spaces) that takes up almost the entire cell.

NRBCs and Howell Jolly body

NRBCs and Howell Jolly body

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