Staphylococcus Saprophyticus

  • Staphylococcus saprophyticus is a Gram-positive, coagulase-negative bacterium.
Staphylococcus saprophyticus gram stain

Staphylococcus saprophyticus gram stain

  • S. Saprophyticus is a common cause of community-acquired urinary tract infections.
  • S. saprophyticus is found in the normal flora of the female genital tract and perineum. S. saprophyticus causes 10-20% of urinary tract infections (UTIs). In females 17–27 years old, it is the second most common cause of community-acquired UTI, after Escherichia coli.
  • Sexual activity increases the risk of S. saprophyticus UTI because bacteria are displaced from the normal flora of the vagina and perineum into the urethra. Most cases occur within 24 hours of sex, earning this infection the nickname “honeymoon cystitis”.

Laboratory diagnosis:

  • Urinalysis and Urine Culture
  • Gram-Positive Bacteria
  • Catalase Test is Positive
  • Coagulase Test is Negative
  • Lastly, S. saprophyticus is differentiated from S. epidermidis which another species Staphylococcus genus by testing for susceptibility to the antibiotic novobiocin. S. saprophyticus is novobiocin-resistant, whereas S. epidermidis is novobiocin-sensitive.
Staphylococcus saprophyticus

Staphylococcus saprophyticus


  • S. saprophyticus urinary tract infections are usually treated with trimethoprim-sulfamethoxazole or with a quinolone
Source: Wikipedia & Others

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