- Top left frame: Monocyte with an irregular outline, gray cytoplasm containing a few azurophilic granules and vacuoles, and a nucleus with an open or lacy chromatin distribution.
- Lower left frame: 1 Plasmacytoid Lymphocyte. Compare its basophilic cytoplasm with the pale gray cytoplasm of the monocyte in the top left frame and its coarse chromatin with that in the monocyte.
- Right frame: A partially distorted lymphocyte which contains several large azurophilic granules. It is a Large Granular Lymphocyte (LGL). Below it is a large cell that could be a monocyte or reactive lymphocyte. The cytoplasm is colorless except at the periphery; a common feature of reactive lymphocytes. The evenly distributed nuclear chromatin is slightly more dense than usual in monocytes but less dense than in reactive lymphocytes. Viral infection blood – 100X
Differentiating Monocytes from Large Lymphocytes
