Microscopic Morphologic Features of Yeast

The cells shown in Image below are arthroconidia, some showing buds coming off of adjacent corners. This feature is diagnostic for Trichosporon species.

Trichosporon mucoides -Chains of arthroconidia (AC) have developed from the hyphae.  Lateral blastoconidia (BC) are present, as the name implies, on the sides of the arthconidial chains or hyphae.

Trichosporon mucoides -Chains of arthroconidia (AC) have developed from the hyphae. Lateral blastoconidia (BC) are present, as the name implies, on the sides of the arthconidial chains or hyphae.

Trichosporon asahii -a hyphal element running from right to left through the center of the photo can be seen disarticulating (fragmenting) into barrel-shaped arthroconidia.

Trichosporon asahii -a hyphal element running from right to left through the center of the photo can be seen disarticulating (fragmenting) into barrel-shaped arthroconidia.

Trichosporon inkin hyphae fragmentation to arthroconidia

Trichosporon inkin hyphae fragmentation to arthroconidia


The yeast cells of Cryptococcus neoformans tend to be spherical, irregular in size, produce a single bud attached by a hair like connector and are surrounded by polysaccharide capsules, as illustrated in Image below.

Cryptococcus neoformans

Cryptococcus neoformans


Candida species, including C. albicans, produce single buds that tend to elongate, forming the precursor of what will be a pseudohypha. Thus, the cell shown in Image below can be suspected of being a Candida species because of the distinctly elongated bud.

Candida sp showing budding yeasts and pseudohyphae

Candida sp showing budding yeasts and pseudohyphae


The cells shown in Image below are regular in size, have a spherical bud attached by a connector wider than seen in C. neoformans, and no surrounding capsular material. This yeast cell is most consistent with Candida (formerly Torulopsis) glabrata.

Candida glabrata yeasts

Candida glabrata yeasts

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